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Sertoli cells assist in the production of sperm in the male reproductive system. This book provides a state-of-the-art update on the topic of sertoli cells and male reproduction. It addresses such highly topical areas as stem cells, genomics, and molecular genetics, as well as provides historical information on the discovery of this type of cell, and the pathophysiology of male infertility.* Presents the state-of-the-art research on topics such as stem cell research, transplantation and genomics* Includes contributions from leaders in the field, including several members of the Nat

Sertoli cells --- Spermatozoa. --- Physiology.

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Cell metabolism --- Cells --- Metabolic Diseases --- Homeostasis --- metabolism --- Metabolic Diseases. --- Homeostasis. --- Cellules --- Cell metabolism. --- Métabolisme cellulaire. --- metabolism. --- Métabolisme --- Autoregulation --- Diseases, Metabolic --- Thesaurismosis --- Disease, Metabolic --- Metabolic Disease --- Thesaurismoses --- Metabolism --- Cell --- Cell Biology --- Cellular control mechanisms --- Métabolisme cellulaire. --- Métabolisme --- Cytology --- cells. --- metabolic diseases. --- homeostasis. --- biochemistry --- physiology --- anabolism --- biocatalysis --- biosynthesis --- carbohydrate metabolism --- carbon metabolism --- catabolism --- catabolite repression --- copper metabolism --- dealkylation --- energy metabolism --- hormone metabolism --- lipid metabolism --- metabolic detoxification --- metabolic sequestration --- mineral metabolism --- nitrogen metabolism --- pharmacokinetics --- protein metabolism --- steroid metabolism --- vitamin metabolism --- water metabolism --- metabolic flux analysis --- metabolic studies --- metabolites --- metabolome --- metabolomics --- oxidative stress --- cell biology --- acinar cells --- adipocytes --- aleurone cells --- antigen-presenting cells --- bacteriocytes --- blood cells --- bone marrow cells --- bundle sheath cells --- chondrocytes --- chromaffin cells --- chromatophores --- coelomocytes --- cultured cells --- endothelial cells --- epithelial cells --- eukaryotic cells --- fibroblasts --- germ cells --- giant cells --- gonadotropic cells --- granulosa cells --- guard cells --- hemocytes --- hepatocytes --- islets of Langerhans --- keratinocytes --- kidney cells --- Leydig cells --- luteal cells --- mast cells --- myocytes --- neoplasm cells --- neurosecretory cells --- nurse cells --- osteoblasts --- osteoclasts --- phagocytes --- plant root cells --- prokaryotic cells --- Schwann cells --- Sertoli cells --- somatic cells --- splenocytes --- spores --- stem cells --- stromal cells --- tenocytes --- teratocytes --- thecal cells --- vegetative cells --- artificial cells --- cell transplantation --- cell viability --- cellular microenvironment --- physiological regulation --- autoregulation --- glucagon-like peptide 2 --- glucoregulation --- glucose tolerance tests --- metabolic disorders --- noninfectious diseases --- acidosis --- alkalosis --- calcinosis --- carbohydrate metabolism disorders --- dehydration (animal physiology) --- developmental orthopedic disease --- diabetes --- hypercalcemia --- hyperinsulinemia --- hyperkalemia --- hyperketonemia --- hypocalcemia --- hypokalemia --- hypomagnesemia --- hyponatremia --- inherited metabolic diseases --- iron overload --- ketonemia --- ketonuria --- lipid metabolism disorders --- osteomalacia --- refeeding syndrome --- uremia --- malnutrition --- Metabolisme cel·lular --- Citologia --- Homeòstasi

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Unwanted childlessness affects approximately one in six couples worldwide. - though the exact proportion of the predominant cause of the problem remains controversial, according to the World Health Organization (WHO), in nearly 40% of cases the cause can be attributed to the female, in 20% to the male, in 25% to both, and in 15% the cause remains unknown. Based on these ?gures, the - cidence of male factor infertility in the general population is approximately 7%. The majority of these men, approximately 30%, experience irreversible idiopathic infertility and cannot father children without some form of medical intervention. Male factor infertility, in addition, may be caused by testicular germ cell cancer, which is known to represent the most common cancer among young men, aged 15 to 35 years, in Western industrialized countries. The number of affected men has increased dramatically over the past 50 years. There is now growing evidence that human testicular germ cell cancer originates from fetal germ cells exhibiting an aberrant programme of gene expression, and tumour progression may be favoured by an aberrant Sertoli cell-germ cell communication.

Sertoli cells. --- Germ cells. --- Spermatogenesis. --- Infertility, Male. --- Male infertility --- Male sterility --- Sterility, Male --- Generative organs, Male --- Infertility --- Formation of spermatozoa --- Spermatozoa --- Gametogenesis --- Gametocytes --- Germ-line cells --- Germline --- Reproductive cells --- Sex cells --- Cells --- Germplasm resources --- Cells of Sertoli --- Sertoli's cells --- Sustentacular cells --- Testis --- Diseases --- Formation --- Medicine. --- Biomedicine general. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general. --- Medicine --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research

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Embryonic stem cells --- Human embryo --- Embryo, Human --- Embryology, Human --- Research.

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The attitude to the possibility of regeneration in mammals has changed in recent years to one of cautious optimism that the endogenous mechanisms can be exploited for the medical armentarium. In this volume leading experts discuss the molecular, in vivo and clinical aspects of the use of stem cells in various disease contexts. With the current excitement in the research and clinical communities over the potential of regenerative medicine it is hoped that novel therapies will emerge that target intractable degenerative diseases. The book contains accounts of the latest advances in stem cell biology from the foremost researchers in the field. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique in combining basic and applied approaches.

Stem cells --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Cytology. --- Developmental biology. --- Neurology. --- Cardiology. --- Cell Biology. --- Developmental Biology. --- Heart --- Internal medicine --- Medicine --- Nervous system --- Neuropsychiatry --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Cell biology --- Cellular biology --- Cytologists --- Diseases --- Cell biology. --- Neurology . --- Regeneration (biologie)